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In cancer cells, enhancer hijacking mediated by chromosomal alterations and increased deposition of acetylated histone H3 lysine 27 (H3K27ac) can support oncogene expression. However, how the chromatin conformation of enhancer-promoter interactions is affected by these events is unclear. In a new study, scientists at the EPFL and UNIL used a new algorithmic approach to examine…

Launched by NASA on September 5, 1977, Voyager 1 spacecraft is the most distant human-made object in space. Having operated for 43 years, the spacecraft still communicates with the Deep Space Network to receive routine commands and transmit data to Earth. In 2012, the spacecraft crossed the heliopause, the solar system’s border with interstellar space,…

Studies of autistic children suggest that restricted eating, reduced physical activity, and sleep disorders are common. However, there are no studies to describe the diet, exercise, and sleep patterns of autistic adults or consider relationships between lifestyle behaviors and the widely reported increased risks of obesity and chronic conditions. In Cambridge, scientists at the Autism…

Human somatic cells commonly have 46 chromosomes, which together convey the genetic information. These chromosomes are first united at fertilization, 23 from the dad’s sperm and 23 from the mother’s egg.  After fertilization, the parental chromosomes at first exist in two separate compartments, known as pronuclei. These pronuclei gradually move towards one another until they…